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Tobacco Regulatory Science and Policy

The TSET Health Promotion Research Center conducts groundbreaking research to help inform tobacco regulatory science and policy on a broad range of issues

Regulatory science focuses on ensuring that scientifically valid techniques, tools, and models are available to evaluate products and, subsequently, to inform regulatory actions that promote optimal health outcomes (Hamburg, 2010; Norman, 2012).

Search HPRC Policy Related Publications

The faculty at the TSET Health Promotion Research Center (HPRC) currently have written or co-written over 90 policy related publications. You may search by any of the descriptors below. To refine your search, you may search by multiple descriptors.

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Tobacco regulatory research at HPRC:

Dr. Lurdes Queimado examines the health effects of traditional and emerging tobacco products using a broad combination of biological tools, including a novel DNA damage assay (q-PADDA) developed in her laboratory.

Dr. Amy Cohn examines the effects of menthol-flavored tobacco products and low nicotine cigarettes on addiction outcomes.

Dr. Evan Floyd examines product design characteristics and standards.

Dr. Jason Oliver examines novel pharmacological, behavioral, and technology-based interventions for tobacco use, as well as how the tobacco regulatory environment contributes to the etiology of nicotine dependence.

Dr. Erin Vogel examines the effects of tobacco-related social media content and marketing claims on young people's perceptions of and intentions to use tobacco products.

Tobacco Industry Interference and Deception

The HPRC Tobacco Industry Interference and Deception Exposed, or "TIIDE" study, seeks to determine the impact of efforts by tobacco companies to defeat effective tobacco control policy and promote ineffective policy of their own design. The TIIDE study also examines changes in policy-related awareness and attitudes after exposure to court-ordered "corrective statements" now being published by major U.S. tobacco companies

Key findings from the TIIDE study are presented in the following articles and reports:

The HPRC Regulatory Science Laboratory includes Clinical and Experimental laboratories

The Clinical laboratory 

Includes 4 negative pressure rooms and 2 control rooms for conducting clinical human laboratory research. The control rooms allow for continuous monitoring of participants and are equipped with video capabilities. The clinical laboratory is equipped with diverse topography registries (e.g., e-cig, tobacco, hookah) for use in lab as well as in field research. Routine collection of exhaled breath, saliva, blood, urine, and buccal samples provides support for diverse FDA and NIH supported grants and assures that scientifically valid tools are used to inform regulatory actions.

The HPRC Experimental Laboratory

Adjacent to the Clinical laboratory, supports the processing, analysis, and storage of biological samples collected at the Clinical Laboratory. Analysis performed at this laboratory include CO, nicotine, and cotinine measurements, and verification of drug use abstinence. Over 3,000 samples were processed at this state-of-the-art laboratory in FY22. After initial validation, samples stored at the HPRC Experimental Laboratory can be distributed to diverse other experimental laboratories for studies such as DNA damage and mutation analysis, RNA sequencing, gene and protein expression, and inflammation studies.