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Thanh C Bui, MD, DrPH

Thanh C. Bui, MD, DrPH

Associate Professor, Department of Family and Preventive Medicine

thanh-c-bui@ou.edu

Thanh C. Bui, MD, DrPH, is an Associate Professor in the Department of Family and Preventive Medicine, and a member of the Stephenson Cancer Center. Dr. Bui has an interdisciplinary background in medicine, global health, health promotion research and cancer prevention research. Dr. Bui's main research interest focuses on behavioral interventions for cancer prevention and control in high-risk populations, including immunizations against oncogenic viruses and tobacco cessation.

His current NCI-funded research projects use mobile health (mHealth) technology to help vulnerable patient populations quit smoking cigarettes in the United States, in Cambodia, and in Lao People's Democratic Republic. Two other studies examine the relationships between tobacco use, marijuana use, oncogenic (co)infections, and several health outcomes among Americans. Other research interests of Dr. Bui include sexual health promotion to prevent cancers (e.g., HPV vaccination) and the application of innovation generation tools to promoting cancer prevention behaviors.

He has extensive experience in working with vulnerable high-risk populations, such as people living with HIV/AIDS, sex workers, and people with low socioeconomic status. He also has strong partnerships with senior investigators and health practitioners in developing countries in Southeast Asia, such as Vietnam, Lao PDR and Cambodia.

Education:

Degree-Granting Institutions

  • The University of Texas Health Science Center, Houston, TX, DrPH, 2010, Health Promotion and Behavioral Sciences, Health Economics, Epidemiology, Global Health
  • Yale University, School of Public Health, New Haven, CT, MPH, 2006, Global Health
  • Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam, MD, 2002 (US equivalency, as evaluated by the World Education Services and Foundation for International Services)

Postgraduate Training

  • Postdoctoral Fellowship, Innovation in Cancer Prevention Research Training Program, The University of Texas Health Science Center at Houston, Houston, TX, United States. 2012 - 2014
  • Postdoctoral Fellowship, Center for International Training on AIDS Research, The University of Texas Health Science Center at Houston, Houston, TX, United States. 2010 - 2012

https://www.ncbi.nlm.nih.gov/myncbi/thanh.bui.1/cv/71337/

Funding:

Active:

U01CA294811  (MPI: Bui, Vidrine, Xangsayarath)
08/12/2024–07/31/2029
Implementing Sustainable mobile health Technology to Optimize smoking cessation Program for Lao people with HIV (I-STOP)
The purpose of this research project is to compare 2 smoking cessation implementation strategies in 8 antiretroviral therapy (ART) clinics in the 5 most populous provinces/regions across Laos, using a hybrid type-2 pragmatic effectiveness-implementation study and a parallel cluster randomized trial design. Specifically, the study will compare an Ask-Advice-Connect (AAC) approach paired with an mHealth automated tobacco treatment program to an AAC approach paired with less resource intensive printed self-help material. The project has the potential to transform HIV care delivery and tobacco treatment throughout Laos to reduce tobacco-related cancers and other morbidities.
Total: $3,187,275 (Direct: $2,720,795)

OUHealth Harold Hamm Diabetes Center Novel Pilot Grant  (PI: Nguyen, Co-I: Bui)
07/01/2024–06/30/2026
Implementing A Culturally Adapted mHealth Intervention at Community Clinics.
The purpose of this mixed-methods pilot study is to assess the preliminary efficacy and implementation feasibility of our fully automated messaging program to support self-management in Vietnamese patients with diabetes in Oklahoma and Texas.
Role: Co-investigator.
Total (direct): $140,000

U01 CA261598 (MPI: Bui, Vidrine)
09/17/2021–09/16/2026
Ending Tobacco Use through Interactive Tailored Messaging for Cambodian People Living with HIV/AIDS (EndIT).
This research project aims to evaluate efficacy and cost-effectiveness of our theoretically and empirically based mobile health (mHealth) smoking cessation intervention for smokers living with HIV in Cambodia. This mHealth approach includes a fully automated, interactive, personalized, smartphone-delivered intervention for behavioral treatment.
Total: $3,614,445 (Direct: $2,480,787)

R33CA253600 (R21/R33) (PI: Bui)
09/01/2020–08/30/2026
Mobile Health Technology for Personalized Tobacco Cessation Support in Laos (Support Laos)
This research project aims to adapt and evaluate the efficacy of our theoretically and empirically based mobile health (mHealth) technology to help people quit smoking cigarettes in Lao People’s Democratic Republic.
Total: $ 1,121,290 (Direct: $ 843,863).

Completed:

GRF00005968 (PI: Nguyen, Co-I: Bui)
New Investigator Grant  - Presbyterian Health Foundation
07/01/2022–06/30/2024
mHealth Intervention for Self-Management among Vietnamese Americans with Type 2 Diabetes (SMART-D): A Feasibility Study.
This study aims to pilot a multilevel, multicomponent, culturally tailored Vietnamese intervention project to provide diabetes education, health behavior change support, and emotional support through secure, patient-facing mobile health technology to help patients understand the disease process, gain skills to manage their condition, and adopt a healthy lifestyle.
Total (direct): $100,000

2023 PHF Research Support Award (PI: Bui)
07/03/2023–07/02/2024
Mobile Health Technology for Personalized Tobacco Cessation Support in Laos (Support Laos) - PHF Research Support Award
The PHF Research Support Grant Program provides stipend support for a senior doctoral graduate student (Shweta Kulkarni) working on Dr. Bui’s externally funded research project (Support Laos) in order to accelerate the project’s progress, increase the number of publications, and position the project for continued external funding. Nested in Dr. Bui’s Support Laos project, Ms. Kulkarni’s proposed dissertation research project aims to examine the correlation between COVID-19-related stress and smoking cessation in Lao PDR.
Total: (Direct): $15,000

Oklahoma Shared Clinical & Translational Resources (OSCTR) Pilot Award (MPI: Bui, Braun)
01/17/2023–06/30/2024
Mobile health-based motivational interviewing to promote SARS-CoV-2 vaccination in Oklahomans (CoVacc)
This study aims to evaluate the preliminary efficacy and acceptability of our mHealth-based motivational interviewing intervention to promote SARS-CoV-2 vaccination in an Oklahoman rural population.
Total (direct): $50,000

2023 PHF Bridge Grant (PI: Bui)
10/01/2023–09/30/2024
Empower Patient with HPV-associated Disease to Promote HPV Vaccination (Empower) – PHF Bridge Grant component
The purpose of the PHF Bridge Grant program is to provide funding of limited duration to OUHSC faculty members who have submitted applications (requesting >$750,000 in total direct costs) to extramural funding agencies (e.g., NIH, DoD, PCORI, or ARHQ), which have been reviewed and scored but not funded. The PHF Bridge Grant support provides a mechanism through which investigators can address scientific issues raised in peer review critiques, generate essential preliminary data, and submit more competitive revised applications. In this PHF Bridge Grant, Dr. Bui’s team plans to expand their current cervical cancer–based interactive HPV vaccination education program (IHVEP) for use by patients with oropharyngeal dysplasia or cancer, which will help to strengthen their R01 resubmission.
Total (direct): $97,666

R01CA243552 (PI: Damon Vidrine) (Co-I, Site PI: Bui)
09/01/2019–08/31/2024
Randomized Trial of Automated Video-Assisted Smoking Treatment for People Living with HIV
The purpose of this randomized controlled trial is to evaluate a fully automated smartphone smoking-cessation intervention for HIV-positive smokers.

3R21CA253600-02S1  (PI: Bui)
09/01/2021–08/31/2022
Mobile Health Technology for Personalized Tobacco Cessation Support among Cancer Survivors in Laos (SurvLaos)
This pilot randomized controlled trial aims to adapt and evaluate the efficacy of our theoretically and empirically based mobile health (mHealth) technology to help cancer survivors and their caregivers quit smoking tobacco in Lao People’s Democratic Republic.
Total: $99,846 (Direct: $76,293).

Stephenson Cancer Center - Pilot Award  (PI: Bui)
07/01/2018–04/30/2022
Promoting human papillomavirus vaccine uptake in high-risk adults
This pilot study aims to determine the preliminary efficacy of an innovative, theory-based approach that combines partner referral and peer-driven intervention to increase human papillomavirus vaccine uptake in eligible high-risk adults in Oklahoma City, OK, USA.
Total: $40,000 (Direct: $40,000)

NCORP-Gogoi-GY7, NRG Oncology - NCI Community Oncology Research Program (NCORP) Pilot Award (PI: Gogoi, Radhika)
01/15/2021–06/30/2022
Relational Agents in HPV Vaccine Education
This project aims to explore the efficacy of a computerized simulated interactable healthcare provider in educating survivors of an HPV related disease (e.g., cervical cancer) about the importance of HPV vaccination and engaging them in promoting HPV vaccination. Study sites include the NCI-designated Stephenson Cancer Center at the University of Oklahoma Health Sciences Center and the Karmanos Cancer Institute (KCI) at Wayne State University.
Role: Co-investigator, Site PI

NCI SBIR PHS 2021-1      (PI: Amarasingham)
09/16/2021–06/15/2022
Screening for Social Determinants of Health and Interventions to Improve Outcomes in the Cancer Patient Population.
The goal of this project is to design and launch an Information Technology (IT) platform that enables easy incorporation of Social Determinants of Health data into cancer patients’ electronic health records in order to improve coordination of care for cancer patients in multiple cancer centers across the US.
Role: Co-investigator

Presbyterian Health Foundation - Seed Grant (PI: Bui)
07/01/2018–06/30/2020
Using partner referral to increase human papillomavirus vaccine uptake
The purpose of this mixed-methods pilot study is to determine the feasibility of an innovative, evidence-based approach—partner referral—to increase HPV vaccine uptake in people living with HIV in Oklahoma City, OK, USA.

Select Publications:

  1. Bui TC, Piñeiro B, Vidrine DJ, Wetter D, Frank-Pearce SG, Vidrine, JI. Quitline treatment enrollment and cessation outcomes among smokers linked with treatment via Ask-Advise-Connect: Comparisons among smokers with and without HIV. Nicotine Tob Res. 2019;ntz227. [Epub ahead of print]. DOI: 10.1093/ntr/ntz227. PMID: 31811295.
  2. Sopheab H, Suy S, Chhea C, Chhit S, Mun P, Bui TC. Psychological distress among Cambodian people who use drugs. Drug Alcohol Rev. 2019 Oct 23. DOI: 10.1111/dar.13000. [Epub ahead of print]. PMID: 31646699.
  3. Xangsayarath P, Douangvichith D, Siengsounthone L, Phandouangsy K, Tran LT, Bui TC. Tobacco use in Lao People’s Democratic Republic: Results from the 2015 National Adult Tobacco Survey. Tob. Prev. Cessation. 2019;5(September):31. DOI:10.18332/tpc/112248. PMID: 32411894; PMCID: PMC7205112.
  4. Bui TC, Scheurer ME, Pham VT, Tran LT, Hor LB, Vidrine DJ, Ross MW, Markham CM. Intravaginal practices and genital human papillomavirus infection among female sex workers in Cambodia. J Med Virol. 2018 Nov;90(11):1765–1774. doi: 10.1002/jmv.25268. Epub 2018 Aug 13. PMID: 30016541. PMCID: PMC6158050.
  5. Bui TC, Tran LT, Thai TN, Shete SS, Vidrine DJ, Sturgis EM. Prevalence of and risk factors for oral human papillomavirus infection with multiple genotypes in the United States. Sex Transm Dis. 2017 Mar;44(3):166–172. doi: 10.1097/OLQ.0000000000000563. PMID: 28178115.
  6. Bui TC, Thai TN, Tran LT, Shete SS, Ramondetta LM, Basen-Engquist KM. Association Between Vaginal Douching and Genital Human Papillomavirus Infection Among Women in the United States. J Infect Dis. 2016 Nov 1;214(9):1370-1375. Epub 2016 Aug 23. PMID: 27553042.
  7. Bui TC, Tran LT, Hor LB, Scheurer ME, Vidrine DJ, Markham CM. Intravaginal Practices in Female Sex Workers in Cambodia: A Qualitative Study. Arch Sex Behav. 2016 May;45(4):935-43. doi: 10.1007/s10508-015-0675-1. Epub 2016 Jan 7. PMID: 26742508; PMCID: PMC4821710.
  8. Bui TC, Krieger HA, Blumenthal-Barby JS. Framing effects on physicians' judgment and decision making. Psychol Rep. 2015 Oct;117(2):508-22. doi: 10.2466/13.PR0.117c20z0. Epub 2015 Oct 7. PMID: 26444837.
  9. Bui TC, Tran LT, Markham CM, Huynh TT, Tran LT, Pham VT, Tran QM, Hoang NH, Hwang LY, Sturgis EM. Self-reported oral health, oral hygiene, and oral HPV infection in at-risk women in Ho Chi Minh City, Vietnam. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Jul;120(1):34-42. doi: 10.1016/j.oooo.2015.04.004. Epub 2015 Apr 24.  PMID: 26093681; PMCID: PMC4475846.
  10. Bui TC, Tran LT, Ross MW, Markham CM. Douching practices among female sex workers in Phnom Penh, Cambodia. Int J STD AIDS. 2015 Mar;26(4):238-42. doi: 10.1177/0956462414533098. Epub 2014 May 8. PMID: 24810219.
  11. Bui TC, Nyoni JE, Ross MW, Mbwambo J, Markham CM, McCurdy SA. Sexual motivation, sexual transactions and sexual risk behaviors in men who have sex with men in Dar es Salaam, Tanzania. AIDS Behav. 2014 Dec;18(12):2432-41. doi: 10.1007/s10461-014-0808-x. PMID: 24890184; PMCID: PMC4229400.
  12. Bui TC, Markham CM, Ross MW, Mullen PD. Examining the association between oral health and oral HPV infection. Cancer Prev Res (Phila). 2013 Sep;6(9):917-24. doi: 10.1158/1940-6207.CAPR-13-0081. Epub 2013 Aug 21. PMID: 23966202.
  13. Bui TC, Markham CM, Tran LT, Beasley RP, Ross MW. Condom negotiation and use among female sex workers in Phnom Penh, Cambodia. AIDS Behav. 2013 Feb;17(2):612-22. doi: 10.1007/s10461-012-0369-9. PMID: 23196858; PMCID: PMC3562386.
  14. Bui TC, Markham CM, Ross MW, Williams ML, Beasley RP, Tran LT, Nguyen HT, Le TN. Dimensions of gender relations and reproductive health inequity perceived by female undergraduate students in the Mekong Delta of Vietnam: a qualitative exploration. Int J Equity Health. 2012 Oct 24;11:63. doi: 10.1186/1475-9276-11-63. PMID: 23095733; PMCID: PMC3511059.
  15. Bui TC, Markham CM, Ross MW, Williams ML, Beasley RP, Tran LT, Nguyen HT, Le TN. Perceived gender inequality, sexual communication self-efficacy, and sexual behaviour among female undergraduate students in the Mekong Delta of Vietnam. Sex Health. 2012 Sep;9(4):314-22. doi: 10.1071/SH11067. PMID: 22877589; PMCID: PMC3435105.

Link to Published Work